Diabetes control with Metformin-Astrapharm
Since 1991, World Diabetes Day is a global campaign which aims to raise the population awareness of diabetes mellitus, the causes of its development and prevention methods.
The day itself marks the birthday of Frederick Banting who received the Nobel Prize in Physiology or Medicine for the discovery of insulin in 1923.
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, caused by absolute or relative insulin deficiency. There are two types of diabetes: insulin-dependent (type 1) and non-insulin-dependent (type 2). The disease is associated with metabolism disruption, long-term damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart, and blood vessels.
The exact causes that trigger the autoimmune reaction in type 1 diabetes are still not understood, so it is almost impossible to prevent the disease. As for type 2 diabetes, the disease is strongly associated with obesity and sedentary lifestyle, and it can be prevented in 80% of cases by following simple rules of a healthy lifestyle:
- maintain a healthy weight;
- be physically active and devote at least 150 minutes per week to moderate-intensity physical exercise;
- maintain a balanced diet, reduce saturated fat and sugar intake;
- break with bad habits.
When a diagnosis is accurate and made in a timely manner, the likelihood of developing severe complications, such as myocardial infarction, stroke, diabetic retinopathy followed by blindness, nephropathy with renal failure, and lower extremity arterial disease, is significantly reduced. In regard to this matter, in 2018, Astrapharm introduced an oral hypoglycemic drug Metformin-Astrapharm to the Ukrainian pharmaceutical market.
The active ingredient of the drug is metformin. It reduces hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Metformin-Astrapharm comes in film-coated tablets, that contain 500, 850 or 1000 mg of metformin hydrochloride.
The drug is dispensed on prescription only.
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