- active substance: lisinopril;
- 1 tablet contains lisinopril 5 mg or 10 mg or 20 mg
- excipients: calcium hydrogen phosphate, lures (E 421), corn starch, magnesium stearate, colloidal silicon dioxide.
Dosage form. Pills.
Basic physical and chemical properties: flat-cylindrical white tablets with beveled edges and a notch.
There are 10 tablets in a blister, 1, 2, 3, 6, 9 or 10 blisters in a box.
Chronic heart failure.
Acute myocardial infarction in patients with stable hemodynamic parameters (systolic blood pressure> 100 mm Hg).
Diabetic nephropathy in diabetes mellitus (in patients with insulin-dependent type II diabetes mellitus).
Hypersensitivity to lisinopril, other components of the drug or other ACE inhibitors.
History of angioedema (including after the use of ACE inhibitors, idiopathic and hereditary edema).
Aortic or mitral stenosis or hypertrophic cardiomyopathy with severe hemodynamic disturbances.
Bilateral renal artery stenosis or stenosis of a solitary kidney artery; acute myocardial infarction with unstable hemodynamics; cardiogenic shock concomitant use of the drug and high-throughput membranes with polyacrylonitrile sodium-2-methylalyl sulfonate (for example, AN 96) for urgent dialysis; patients with serum creatinine levels ≥ 220 μmol / L.
Simultaneous use of aliskiren drugs in patients with diabetes mellitus or impaired renal function (GFR <60 ml / min / 1.73 m2).
The tablets are taken orally 1 time per day, preferably at the same time, regardless of the meal. The daily dose is selected individually, depending on the patient’s response and blood pressure indicators.
The drug is used as monotherapy or in combination with other classes of antihypertensive drugs.
The safety and efficacy of lisinopril in children have not been established, therefore, this age category of patients should not be prescribed.