Atenolol-Astrapharm
Release Forms:
The composition 1 tablets:
- active substance: atenolol;
- 1 tablet contains 50 mg or 100 mg atenolol
- excipients: for tablets 50 mg lactose monohydrate, magnesium stearate corn starch for tablets 100 mg lactose monohydrate, magnesium stearate potato starch.
Dosage form. Tablets
Basic physical and chemical properties: tablets of white or almost white color, round in shape with a biconvex surface and a notch on one side.
10 tablets in a blister; 2, 6, 9 or 10 blisters in a box.
Indications.
- Treatment of arterial hypertension.
- Treatment and prevention of angina attacks (chronic stable and unstable angina, especially in combination with tachycardia and hypertension).
- Cardiac arrhythmia, arrhythmia, sinus tachycardia, prevention of supraventricular tachycardia, paroxysmal supraventricular tachycardia, atrial fibrillation and flutter, ventricular (ventricular arrhythmias), including those caused by increased physical activity;
- Myocardial infarction (treatment and prevention to reduce mortality and reduce the risk of recurrent heart attack).
Contraindications.
Hypersensitivity to atenolol or other β-adrenoceptors, or to any components of the drug
- acute heart failure;
- cardiogenic shock;
- blockade of II and III degrees;
- sinus node weakness syndrome;
- sinoatrial block;
- sinus bradycardia (heart rate less than 45 per minute);
- arterial hypotension (systolic pressure below 90 mm Hg)
- bronchial asthma;
- metabolic acidosis,
- late stages of peripheral circulatory disorders
- concomitant use of MAO inhibitors (except for MAO-B inhibitors);
- untreated pheochromocytoma;
- renal failure
- children’s age.
Application method:
The tablets are swallowed without chewing and washed down with a small amount of liquid before meals, preferably at the same time.
Doses of drug and duration of treatment the doctor set individually depending on the received therapeutic effect.
Myocardial infarction: After oral administration, 50 mg orally and 100 mg 12 hours after injection.
Chronic stable and unstable angina: usually prescribed 100 mg of atenolol 1 time per day or 50 mg, which is taken 2 times.
Hypertension: Treatment is usually started with 100 mg of Atenolol-Astrapharm once daily. For some patients, 50 mg per day is sufficient. The effect is observed in 2 weeks. In case of ineffectiveness, atenolol is used together with diuretics.
Supraventricular (supraventricular) and ventricular (ventricular) arrhythmias: Atenolol-Astrapharm is prescribed 1-2 times a day for 50-100 mg.
The maximum daily dose is 200 mg.
In patients with significant renal impairment, the dose of Atenolol-Astrapharm depends on the level of creatinine clearance (CC): with CC 10-30 ml/min dose is reduced by 2 times (50 mg per day or every other day), and with CC less than 10 ml/min dose is reduced by 4 times compared to normal.
Patients on hemodialysis should use 50 mg of the drug after each dialysis.
This should be done in a hospital setting, as there may be a marked decrease in blood pressure.
Children.
The drug is not used in children.